翻訳と辞書 Words near each other ・ DTC-3 ・ DTCC ・ DTD ・ DTD (TV station) ・ DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase ・ DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase ・ DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase ・ DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase ・ DTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase ・ DTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase ・ DTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase ・ DTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase ・ DTDP-4-amino-4,6-dideoxy-D-glucose transaminase ・ DTDP-4-amino-4,6-dideoxygalactose transaminase ・ DTDP-4-dehydro-6-deoxyglucose reductase ・ DTDP-4-dehydrorhamnose 3,5-epimerase ・ DTDP-4-dehydrorhamnose reductase ・ DTDP-6-deoxy-L-talose 4-dehydrogenase ・ DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) ・ DTDP-dihydrostreptose—streptidine-6-phosphate dihydrostreptosyltransferase ・ DTDP-galactose 6-dehydrogenase ・ DTDP-glucose 4,6-dehydratase ・ DTDP-L-rhamnose 4-epimerase ・ DTE ・ DTE (direct to edit) ・ DTE Energy ・ DTE Energy Electric Company ・ DTE Energy Headquarters ・ DTE Energy Music Theatre ・ DTE80 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク DTDP-4-dehydrorhamnose 3,5-epimerase ： ウィキペディア英語版 DTDP-4-dehydrorhamnose 3,5-epimerase In enzymology, a dTDP-4-dehydrorhamnose 3,5-epimerase () is an enzyme that catalyzes the chemical reaction :dTDP-4-dehydro-6-deoxy-D-glucose $\backslash rightleftharpoons$ dTDP-4-dehydro-6-deoxy-L-mannose Hence, this enzyme has one substrate, dTDP-4-dehydro-6-deoxy-D-glucose, and one product, dTDP-4-dehydro-6-deoxy-L-mannose. This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase. Other names in common use include dTDP-L-rhamnose synthetase, dTDP-L-rhamnose synthetase, thymidine diphospho-4-ketorhamnose 3,5-epimerase, TDP-4-ketorhamnose 3,5-epimerase, dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase, and TDP-4-keto-L-rhamnose-3,5-epimerase. This enzyme participates in 3 metabolic pathways: nucleotide sugars metabolism, streptomycin biosynthesis, and polyketide sugar unit biosynthesis. ==Structural studies== The crystal structure of RmlC from ''Methanobacterium thermoautotrophicum'' was determined in the presence and absence of a substrate analogue. RmlC is a homodimer comprising a central jelly roll motif, which extends in two directions into longer beta-sheets. Binding of dTDP is stabilised by ionic interactions to the phosphate group and by a combination of ionic and hydrophobic interactions with the base. The active site, which is located in the centre of the jelly roll, is formed by residues that are conserved in all known RmlC sequence homologues. The active site is lined with a number of charged residues and a number of residues with hydrogen-bonding potentials, which together comprise a potential network for substrate binding and catalysis. The active site is also lined with aromatic residues which provide favourable environments for the base moiety of dTDP and potentially for the sugar moiety of the substrate. As of late 2007, 14 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , , , , and . 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「DTDP-4-dehydrorhamnose 3,5-epimerase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.